Purpose For people with metabolic syndrome (MetS), altering the macronutrient composition of their diets might ameliorate metabolic abnormalities. The common method of clinical assessment only measures total lipid concentrations but ignores the individual species that contribute to these total concentrations. Thus, to predict the amelioration of MetS following caloric restriction (CR) and the intake of fish oil, we used lipidomics to investigate changes in plasma lipids and identify potential lipid metabolites. Methods Lipidomics was performed …

An abnormal lipid profile is an independent risk factor for cardiovascular diseases. The relationship between vitamin B12 deficiency and lipid profile is inconclusive, with most studies conducted in unhealthy populations. In this study, we aimed to assess the relationship between serum vitamin B12 levels and lipid profiles in a cross-sectional study that included 341 apparently healthy Saudi women, aged 19–30 years, from different colleges at King Saud University, Saudi Arabia. Sociodemographic, anthropometric …

Background Fluid imbalance is associated with various clinical conditions, but the association between elevated extracellular‐water to total‐body‐water (ECW/TBW) ratio, an indicator of fluid balance, and cognitive impairment is unknown. We aimed to investigate relationship between ECW/TBW ratio and cognitive function in type 2 diabetes mellitus. Methods This study was a cross‐sectional design, comparing 1233 patients aged 61.4±8.0 years from the Singapore Study of Macro‐angiopathy and Micro‐vascular Reactivity in Type …

Purpose We aimed to investigate the characteristics of kidney disease in severely obese Japanese patients with type 2 diabetes mellitus (T2DM). Methods This was a cross-sectional study of severely obese patients (body mass index≥ 35 kg/m 2) with T2DM treated at Jinnouchi Hospital, Kumamoto, Japan. Results A total of 3128 T2DM patients visited the hospital during the survey period, of whom 55 patients (1.7%) were severely obese and 50 patients were enrolled. In terms of diabetic nephropathy (DN), twenty-five patients were …

Purpose As obesity becomes increasingly prevalent, its impact on fertility has been a subject of great debate. Nearly all prior research is retrospective and evaluates obesity utilizing body mass index (BMI), which may overestimate adiposity in individuals with a greater amount of lean muscle and underestimate adiposity in those with less muscle mass. Methods We prospectively evaluated 2013 couples undergoing infertility treatment with in vitro fertilization (IVF). Percent body fat (% BF) was measured by use of a bioelectric …

Background The existence of metabolic adaptation, following weight loss, remains a controversial issue. To our knowledge, no study has evaluated the role of energy balance (EB) in modulating metabolic adaptation. Objectives The aim of this study was to determine if metabolic adaptation, at the level of resting metabolic rate (RMR), is modulated by participants' EB status. A secondary aim was to investigate if metabolic adaptation was associated with weight regain. Methods Seventy-one individuals with obesity (BMI: 34.6±3.4 …

… The inverse relationship between obesity and serum vitamin D concentrations may have several explanations, including … studies have found a higher prevalence of vitamin D deficiency among men than … that a gender difference in the prevalence of vitamin D deficiency is related …

The double burden of malnutrition is an emerging public health concern nowadays which a correlation with obesity. This study aimed to examine the relationship between resting metabolic rate (RMR) and dietary intake of zinc, vitamin C, and riboflavin in overweight and obese women. The RMR/FFM showed a significant association with riboflavin (β= 1.59; 95% CI 1.04–23.26, P= 0.04) and zinc (β= 0.78; 95% CI 1.04–4.61, P= 0.03) in the crude model. Moreover, differences in vitamin C and RMR/FFM was marginal significant (β= 0.75; 95% CI …

OBJECTIVE: To correlate anthropometric measurements, lipid profile, cardiorespiratory fitness, and visceral adiposity index (VAI) in sedentary obese older women. METHODS: Twenty-seven insufficiently active and overweight older women were included in this cross-sectional study. We evaluated their anthropometric profile (body weight and stature, body mass index, waist and hip circumferences) and body composition (fat mass, body fat percentage, and musculoskeletal mass). Venous blood samples were analyzed for high and …

Introduction Postprandial hyperglycemia is independently associated with many adverse complications, while diets with a low glycemic load are beneficial in improving post-meal glucose levels. This study aims to determine if mobile-app-based low-carbohydrate dietary guidance will reduce exposure to postprandial hyperglycemia in adults with prediabetes. Methods This single-blind, randomized controlled pilot study included 100 participants (39 men; mean age 53.6±11.9 years) and was performed in the PKU Care CNOOC Hospital …