Benefits of Arm Swing Exercise on Cognitive Performance in Older Women with Mild Cognitive Impairment. JEPonline 2016; 19 (6): 123-136. The aim of this study was to determine the effects of arm swing exercise (ASE) training on cognitive performance, oxidative stress, lipid profiles, and aerobic capacity in 24 women (65 to 87 yrs of age) with mild cognitive impairment (MCI). After the Mini-Mental State Examination (MMSE), the subjects were randomly allocated to 12 wks of either a 30-min of supervised ASE per day for …

Background Concepts of successful aging (SA), usual aging (UA), and mild cognitive impairment (MCI) have been developed to identify older adults at high risk of Alzheimer's diseases (AD), however, the predictors have rarely been investigated in a single study. Thus, this study aims to explore the risk factors of MCI as compared to UA and SA among older adults, in a large community based cohort study in Malaysia. Method 1993 subjects from four states in Malaysia were recruited. A comprehensive interview-based questionnaire …

Background. Weight loss in Parkinson's disease (PD) patients is a common but poorly understood manifestation. Several studies have reported that weight changes could be related to motor symptoms, drug side effects, dysphagia, depression, and/or dementia. Weight loss in PD is not a benign phenomenon and it has several clinical and prognostic implications with increased morbidity and mortality. Thus, it is crucial to determine nutritional changes in PD patients in order to prevent malnutrition and improve their quality of life …

Background: This study was conducted to investigate the combined impact of telomere length and mitochondrial DNA (mtDNA) copy number on cognitive function in community-dwelling very old adults. Methods: In total, 186 subjects over 75 years participated in this study. Cognitive function was assessed using the Korean Mini-Mental State Examination, and leukocyte telomere length and mtDNA copy number were measured using real-time polymerase chain reaction methods. Results: Both the fourth quartile of telomere length and …

Objective To determine the risk factors for new neuropathic pain (NeP) after five years in healthy middle-aged and elderly volunteers. Design Prospective longitudinal cohort study (Yakumo study). Setting Clinical evaluation in a health checkup. Subjects A total of 366 people (male N= 146, female N= 220, average age= 63.5 years) who did not have NeP in 2013 were examined. Methods NeP was diagnosed based on a painDETECT questionnaire score≥ 13. Body mass index (BMI), comorbidity, low back pain (LBP), sciatica, physical …

Background: Dehydration may affect cognitive performances as water accounts for 75% of brain mass. The purpose of this study is to investigate the effects of dehydration and water supplementation on cognitive performances, and to explore the changes of brain structures and functions using MRI. Methods and Analysis: A double-blinded randomized controlled trial has been designed and will be implemented among 64 college students aged 18–23 years from Baoding, China. Subjects will be asked to restrict water for 36 h. The first morning …

Abstract Background and Aims: To date, the correlation between sarcopenia, which exists before a stroke, and acute stroke outcome remains partially understood. This study aims to evaluate the skeletal muscle mass deficit using the bioelectrical impedance analysis in patients with acute ischemic stroke. Methods: We enrolled 164 geriatric patients with acute ischemic stroke (108 males and 56 females) who underwent the bioelectrical impedance analysis. We evaluated clinical outcomes and their impact on patients with the skeletal …