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Change of the growth hormone–insulin-like growth factor-I axis in patients with gastrointestinal cancer: related to tumour type

Cancer/ Palliative treatment
Author
Qi Huang et al.
Used Parameters : FFM, SLM,
BFM, Protein

Publication Year : 2005

Country : China

Journal : British Journal of Nutrition

Changes in the growth hormone (GH)–insulin-like growth factor-I (IGF-I) axis, especially acquired GH resistance, develop in many severe illnesses, including cachexia. To study changes in the GH–IGF-I axis in patients with cancer cachexia, biochemical markers and body composition parameters were measured in eighty-eight gastric cancer patients, thirty colorectal cancer patients (subclassified according to the presence or absence of cachexia) and twenty-four healthy control subjects. Fifty-nine patients were defined as cachectic …
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