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Combined impact of telomere length and mitochondrial DNA copy number on cognitive function in community-dwelling very old adult

Neurology
Author
JY Lee et al.
Used Parameters : FFM, PBF
Publication Year : 2017
Country : Korea
Journal : Dementia and Geriatric Cognitive Disorders
Background: This study was conducted to investigate the combined impact of telomere length and mitochondrial DNA (mtDNA) copy number on cognitive function in community-dwelling very old adults. Methods: In total, 186 subjects over 75 years participated in this study. Cognitive function was assessed using the Korean Mini-Mental State Examination, and leukocyte telomere length and mtDNA copy number were measured using real-time polymerase chain reaction methods. Results: Both the fourth quartile of telomere length and …
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