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Dynamics of L-carnitine in plasma and urine in patients undergoing cisplatin chemotherapy

Cancer/ Palliative treatment
Author
Gomi D et al.
Used Parameters : SMM
Publication Year : 2017
Country : Japan
Journal : Chemotherapy
Background and Aims: Several studies have indicated that cisplatin (cis-diamminedichloroplatinum II; CDDP) causes urinary excretion of L-carnitine (LC). However, the underlying cofactors affecting the increased urinary excretion remain unclear. The present study was performed to evaluate the dynamics of LC in plasma and urine after CDDP chemotherapy and to examine the relations with clinical parameters, such as gender, body mass index (BMI), and renal function. Methods: Twenty-two patients treated with CDDP …
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