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Effects of dapagliflozin on body composition and liver tests in patients with nonalcoholic steatohepatitis associated with type

Hepatology
Author
Hiroshi Tobita et al.
Used Parameters : TBW, FFM, SLM, SMM, SMI, BFM, PBF, Protein

Publication Year : 2017

Country : Japan

Journal : Current Therapeutic Research

Background Nonalcoholic steatohepatitis (NASH) is an active form of nonalcoholic fatty liver disease. Risk factors for NASH include type 2 diabetes mellitus (T2DM) and obesity. Sodium–glucose cotransporter 2 (SGLT2) inhibitors used to treat T2DM prevent glucose reabsorption in the kidney and increase glucose urinary excretion. Dapagliflozin is a potent, selective SGLT2 inhibitor that reduces hyperglycemia in patients with T2DM and has been demonstrated to reduce some complications associated with NASH in rodent models …
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