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Exercise training with dietary restriction enhances circulating irisin level associated with increasing endothelial progenitor

Endocrinology
Author
Junhao Huang et al.
Used Parameters : BMI, BFM, PBF

Publication Year : 2017

Country : China

Journal : PeerJ

Objective Circulating endothelial progenitor cells (EPCs) correlate negatively with obesity. Previous studies have shown that exercise significantly restores circulating EPC levels in obese people; however, the underlying mechanisms have not been elucidated. Recently, irisin has been reported to have a critical role in the regulation of EPCs. This exercise-induced myokine has been demonstrated to play a therapeutic role in obesity. In this study, we hypothesized that the increase in circulating irisin may form a link with increasing EPC …
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