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Change in circulating microRNA profile of obese children indicates future risk of adult diabetes

Endocrinology
Author
X Cui et al.
Used Parameters : PBF, FMI
Publication Year : 2017
Country : China
Journal : Metabolism
Purpose Childhood obesity increases susceptibility to type 2 diabetes (T2D) in adults. Circulating microRNAs (miRNAs) in serum have been proposed as potential diagnostic biomarkers, and they may contribute to the progression toward T2D. Here, we investigated the possibility of predicting the future risk of adult T2D in obese children by using circulating miRNAs. Basic Procedures We performed miRNA high-throughput sequencing to screen relevant circulating miRNAs in obese children. The expression patterns of targeted miRNAs …
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