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Switching from low‐dose thiazide diuretics to sodium–glucose cotransporter 2 inhibitor improves various metabolic parameters wi

Endocrinology
Author
T Kimura et al.
Used Parameters : SMM, BFM, VFA
Publication Year : 2017
Country : Japan
Journal : Journal of Diabetes Investigation
Abstract Aims/Introduction Sodium–glucose cotransporter 2 (SGLT 2) inhibitors function to increase urinary glucose excretion and improve glycemic control in individuals with type 2 diabetes mellitus. SGLT 2 inhibitors, as well as diuretics, increase urinary volume, which leads to the reduction of blood pressure. The aim of the present study was to compare the effects of SGLT 2 inhibitor and thiazide diuretic on blood pressure, metabolic parameters and body mass composition. Materials and Methods A total of 31 participants were enrolled …
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