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Effects of ipragliflozin on postprandial glucose metabolism and gut peptides in type 2 diabetes: a pilot study

Endocrinology
Author
H Ueno et al.
Used Parameters : BW, BMI, TBW, Muscle Mass, BFM, PBF
Publication Year : 2018
Country : Japan
Journal : Diabetes Therapy
Introduction Ipragliflozin is a novel antidiabetic drug that inhibits renal tubular sodium-glucose cotransporter-2 (SGLT2). The aim of this study was to evaluate the effects of ipragliflozin on glucose, insulin, glucagon, and gastrointestinal peptide responses to a meal tolerance test, as well as to investigate the glucose-lowering mechanisms of ipragliflozin. Methods Nine Japanese patients with obesity and type 2 diabetes mellitus were treated with ipragliflozin (50 mg/day) for 12 weeks. The postprandial profiles of glucose, insulin …
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