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Does metformin treatment during pregnancy modify the future metabolic profile in women with PCOS?

Gynecology
Author
Underdal et al
Used Parameters : Muscle Mass, BFM, PBF
Publication Year : 2018
Country : Norway
Journal : Journal of Clinical Endocrinology & Metabolism
Context Worldwide, metformin is prescribed to improve pregnancy outcome in polycystic ovary syndrome (PCOS). Metformin may also benefit future health by modulating increased metabolic stress during pregnancy. Objective To investigate whether metformin during pregnancy modified future metabolic health in women with PCOS. Design Follow-up study of a randomized controlled trial that compared metformin with placebo in women with PCOS. Mean follow-up period was 7.7 years (range, 5 to 11 years). Setting Three university …
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