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Quality over quantity? Association of skeletal muscle myosteatosis and myofibrosis on physical function in chronic kidney disea

Nephrology
Author
T. J. Wilkinson et al.
Used Parameters : PBF
Publication Year : 2018
Country : UK
Journal : Nephrology Dialysis Transplantation
Background Chronic kidney disease (CKD) is characterized by adverse changes in body composition, which are associated with poor clinical outcome and physical functioning. Whilst size is the key for muscle functioning, changes in muscle quality specifically increase in intramuscular fat infiltration (myosteatosis) and fibrosis (myofibrosis) may be important. We investigated the role of muscle quality and size on physical performance in non-dialysis CKD patients. Methods Ultrasound (US) images of the rectus femoris (RF) were obtained …
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