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Amino acid-based metabolic panel provides robust prognostic value additive to B-natriuretic peptide and traditional risk factor

Cardiology
Author
CH Wang et al
Used Parameters : SMM
Publication Year : 2018
Country : Taiwan
Journal : Disease Markers
Metabolic disturbances represent functional perturbation in peripheral tissues and predict outcomes in patients with heart failure (HF). This study developed an amino acid-based metabolic panel and sought to see whether this panel could add diagnostic and prognostic value to currently used B-type natriuretic peptide (BNP) measurements. Mass spectrometry and ultra-performance liquid chromatography were performed on 1288 participants, including 129 normal controls and 712 patients at HF stages A to D in the initial cohort and …
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