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The single nucleotide polymorphism PPARG2 Pro12Ala affects body mass index, fat mass, and blood pressure in severely obese pati

Endocrinology
Author
APS Rodrigues et al.
Used Parameters : BMI, FFM, BFM, PBF

Publication Year : 2018

Country : Brazil

Journal : Journal of Obesity

Background. The PPARG2 Pro12Ala (rs1801282) and IL6-174G> C (rs1800795) have important function in body weight regulation and a potential role in obesity risk. We aimed to investigate the association between PPARG2 Pro12Ala and IL6-174G> C variants and the genotypes interaction with body composition, metabolic markers, food consumption, and physical activity in severely obese patients. Methods. 150 severely obese patients (body mass index (BMI)≥ 35 kg/m 2) from Central Brazil were recruited. Body composition …
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