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Intrauterine metformin exposure and offspring cardiometabolic risk factors (PedMet study): a 5–10 year follow-up of the PregMet

Pediatrics
Cardiology
Author
LGE Hanem et al.
Used Parameters : Muscle mass, BFM, PBF

Publication Year : 2019

Country : Norway

Journal : The Lancet Child & Adolescent Health

Background Metformin is increasingly used to treat gestational diabetes and type 2 diabetes in pregnancy, and in attempts to improve pregnancy outcomes in polycystic ovary syndrome and obesity. It passes across the placenta with possible long-term consequences for the offspring. We previously explored the effect of metformin, given to women with polycystic ovary syndrome during pregnancy, on children's growth up to 4 years of age. In this 5–10 year follow-up, we examined the cardiometabolic risk factors in these children. Methods This …
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