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Association of the PNPLA2, SCD1 and leptin expression with fat distribution in liver and adipose tissue from obese subjects

Endocrinology
Author
L De la Cruz-Color et al.
Used Parameters : BW, BMI, BFM, PBF
Publication Year : 2019
Country : Mexico
Journal : Experimental and Clinical Endocrinology & Diabetes
The expansion of adipose tissue is regulated by insulin and leptin through sterol regulatory element-binding protein-1c (SREBP-1c), up-regulating lipogenesis in tissues by Stearoylcoenzyme A desaturase 1 (SCD1) enzyme, while adipose triglyceride lipase (ATGL) enzyme is key in lipolysis. The research objective was to evaluate the expression of Sterol Regulatory Element Binding Transcription Factor 1 (SREBF1), SCD1, Patatin Like Phospholipase Domain Containing 2 (PNPLA2), and leptin (LEP) genes in hepatic-adipose …
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