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The MC4R genetic variants are associated with lower visceral fat accumulation and higher postprandial relative increase in carb

Endocrinology
Author
E Adamska-Patruno et al.
Used Parameters : BFM
Publication Year : 2019
Country : Poland
Journal : European Journal of Nutrition
Purpose The interactions between lifestyle and genetic factors play an important role in obesity development. Mutations in melanocortin-4-receptor (MC4R) gene are one of the most common cause of monogenic obesity, however, the functional effects of polymorphic variants near MC4R gene in general populations remain uncertain. The aim of our study was to analyze whether the common single nucleotide polymorphisms (SNPs) of MC4R gene influence the food preferences, physical activity, body fat content and distribution, as …
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