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Coefficient of Determination between estimated and measured renal function in Japanese patients with sarcopenia may be improved

Nephrology
Physical medicine and Rehabilitation
Author
Nakatani et al.
Used Parameters : FFM, SMM, Segmental FFM
Publication Year : 2019
Country : Japan
Journal : Biologica & Pharmaceutical Bulletin.
Creatinine (Cr) levels are strongly affected by muscle mass, and the estimated glomerular filtration rate (eGFR), a measure based on serum creatinine (SCr), is often overestimated in patients with sarcopenia. To evaluate the coefficient of determination (R 2) between eGFR and the actual measured value, we performed a linear regression analysis of a modified GFR (mGFR: measured Cr clearance× 0.715) and various renal function estimates adjusted for muscle mass in 19 patients with sarcopenia. The eGFR values based on SCr (eGFRcr) …
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