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N-terminal proBNP—marker of cardiac dysfunction, fluid overload, or malnutrition in hemodialysis patients?

Nephrology
Author
John Booth, Jennifer Pinney, Davenport A
Used Parameters : ECW, ICW
Publication Year : 2010
Country : UK
Journal : Clinical Journal of the American Society of Nephrology
Background and objectives: N-terminal probrain type natriuretic peptide (NTproBNP) has been proven to be a valuable biomarker for predicting cardiac events and mortality in the hemodialysis population. However recent reports have suggested that NTproBNP is a marker of volume overload rather than one of cardiac dysfunction. Therefore this study investigated the effect of fluid volume status on NTproBNP. Design, setting, participants, & measurements: Volume status was determined pre-and postdialysis in 72 stable …
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