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Effects of ziprasidone and olanzapine on body composition and metabolic parameters: an open-label comparative pilot study

Physical medicine and Rehabilitation
Author
Subin Park et al.
Used Parameters : FFM, SLM, BFM
Publication Year : 2013
Country : Korea
Journal : Behavioral and Brain Functions
In contrast to olanzapine, ziprasidone has been reported to cause minimal or no weight gain. This study aimed to compare the effects of ziprasidone and olanzapine on weight, body composition, appetite, resting energy expenditure, substrate oxidation, and metabolic parameters in adults with schizophrenia or other psychotic disorders. Twenty adults with schizophrenia or other psychotic disorders were randomized 1: 1 to ziprasidone 20–160 mg/day or olanzapine 5–20 mg/day for 12 weeks. The mean doses during the 12-week …
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