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Moderate diet-induced weight loss is associated with improved insulin sensitivity in middle-aged healthy obese Korean women

Endocrinology
Author
Hye-Ok Lee
Used Parameters : FFM, PBF
Publication Year : 2014
Country : Korea
Journal : Nutrition Research and Practice
RESULTS When calories were reduced by an average of 422 kcal/day for 12 weeks, BMI (-2.7%), body fat mass (-10.2%), and waist circumference (-5%) all decreased significantly (P< 0.05). After calorie restriction, weight, body fat percentage, hip circumference, BP, TC, HDL-C, LDL-C, plasma glucose at fasting, insulin at fasting and 120 min, AUC glu and the insulin area under the curve all decreased significantly (all P< 0.05), while insulin sensitivity (HOMA-IR, QUICKI and Matsuda index) measured by OGTT improved significantly (P< 0.01) …
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