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Safety and efficacy of long‐term tolvaptan therapy for decompensated liver cirrhosis

Hepatology
Author
Kogiso T et al.
Used Parameters : ECW/TBW, Protein
Publication Year : 2015
Country : Japan
Journal : Hepatology Research
Aim Recently, the short‐term efficacy of the vasopressin V2 receptor antagonist tolvaptan for the treatment of ascites in cirrhosis was reported. However, the long‐term effects remain unknown. Here, we report the clinical features of decompensated cirrhosis treated using long‐term tolvaptan therapy, and evaluate its safety and efficacy. Methods Fifty‐five cirrhotic patients hospitalized due to ascites, despite receiving appropriate diuretic treatment, were treated with tolvaptan. We excluded 35 patients due to liver transplant (20.0%), death …
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