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Acute exercise induces FGF21 expression in mice and in healthy humans

Lifestyle Disease
Author
Kook Hwan Kim
Used Parameters : BMI, BFM, PBF

Publication Year : 2013

Country : Korea

Journal : PLoS One

Fibroblast growth factor 21 (FGF21) plays an important role in the regulation of energy homeostasis during starvation and has an excellent therapeutic potential for the treatment of type 2 diabetes in rodents and monkeys. Acute exercise affects glucose and lipid metabolism by increasing glucose uptake and lipolysis. However, it is not known whether acute exercise affects FGF21 expression. Here, we showed that serum FGF21 level is increased in mice after a single bout of acute exercise, and that this is accompanied by …
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