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Sarcopenia is an independent risk factor for non-alcoholic steatohepatitis and significant fibrosis

Physical medicine and Rehabilitation
Author
Koo BK et al.
check : ★
Used Parameters : ASM
Publication Year : 2016
Country : Korea
Journal : Journal of Hepatology
Background & Aims We explored whether sarcopenia is associated with the histological severity of non-alcoholic fatty liver disease (NAFLD), especially non-alcoholic steatohepatitis (NASH) and significant fibrosis. Methods In a biopsy-proven NAFLD cohort, the appendicular skeletal muscle mass (ASM) was measured. Sarcopenia was defined as a ASM/body weight (ASM%) value beyond two standard deviations below the mean for healthy young adults. Results Among the entire set of 309 subjects, the prevalence of …
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