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Reduced protein bound uraemic toxins in vegetarian kidney failure patients treated by haemodiafiltration

Nephrology
Author
Kandouz S et al.
Used Parameters : TBW, ECW
Publication Year : 2016
Country : UK
Journal : Hemodialysis International
Introduction Indoxyl sulfate (IS) and p cresyl sulfate (PCS) are protein bound toxins which accumulate with chronic kidney disease. Haemodiafiltration (HDF) increases middle molecule clearances and has been suggested to increase IS and PCS clearance. We therefore wished to establish whether higher convective clearances with HDF would reduce IS and PCS concentrations. Methods We measured total plasma IS and PCS in a cohort of 138 CKD5d patients treated by On‐line HDF (Ol‐HDF), by high pressure liquid …
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