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Polymorphism of the angiotensin II type 1 receptor A1166C in Korean hypertensive adolescents

Cardiology
Author
Jung Ah Lee et al.
Used Parameters : BFM

Publication Year : 2008

Country : Korea

Journal : Korean Circulation Journal

Results The genotypic frequency of AA was 87.5%, that for adenylate cyclase (AC) was 12.5% and no CC type was detected. The serum homocysteine level was higher in the subjects with the AC genotype than that in the subjects with the AA genotype (11.9±2.9 umol/L vs 17.1±4.2 umol/L, respectively). The carotid IMT of the subjects with the AA genotype was greater than that of the subjects with the AC genotype (5.0±0.1 mm vs 8.0±0.2 mm, respectively). Conclusion In conclusion, the A1166C mutation group had a significantly …
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